Active trials
Read more about the active trials currently enrolling that MedVadis Research is involved with. Contact us anytime if you would like to volunteer or have any questions.
Adult Migraine
Study ID 300
A Phase 4, interventional, open-label trial, investigating the effectiveness of eptinezumab in participants with migraine and previous inadequate response to CGRP-targeting therapies
The main goal of this trial is to learn whether eptinezumab improves migraine symptoms and quality of life of participants with migraine who did not perceive a sufficient improvement during previous treatment with therapies targeting calcitonin gene-related peptide (CGRP).
Medical Conditions:
Migraine
Related Conditions: Migraine
Sex/Gender: Male & Female
Age: 18 Years to 75 Years
Enrolling Now!
Study ID 291
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Ubrogepant for the Preventive Treatment of Menstrual Migraine with an Open-Label Extension
Menstrual migraine (MM) is defined as migraine attacks that occur within the perimenstrual period (PMP) in at least 2 out of 3 menstrual cycles. The PMP is from 2 days before the onset of menstrual bleeding to 2 days after. This study will assess how safe and effective ubrogepant is in treating menstrual migraine. Adverse Events and change in disease activity will be assessed.
Medical Conditions:
Migraine
Related Conditions: Migraine
Sex/Gender: Female
Age: 18 Years and Older
Enrolling Now!
Study ID 301
A Phase 3, randomized, double-blind, placebo-controlled, multicenter, clinical trial with extension period to evaluate the efficacy and safety of Xeomin® injections for the prevention of chronic migraine
In this clinical trial, participants with chronic migraine will receive injections with Xeomin or Placebo into muscles of the head and neck. The purpose is to measure the change in monthly migraine days with Xeomin injections compared to Placebo injections.
Medical Conditions:
Migraine
Related Conditions: Migraine
Sex/Gender: Male & Female
Age: 18 Years and Older
Enrolling Now!
Study ID 302
A Phase 3, randomized, double-blind, placebo-controlled, multicenter, clinical trial with extension period to evaluate the efficacy and safety of Xeomin® injections for the prevention of episodic migraine
In this clinical trial, participants with episodic migraine will receive injections with Xeomin or Placebo into muscles of the head and neck. The purpose is to measure the change in monthly migraine days with Xeomin injections compared to Placebo injections.
Medical Conditions:
Migraine
Related Conditions: Migraine
Sex/Gender: Male & Female
Age: 18 Years and Older
Enrolling Now!
ALS
Study ID 265
To collect, preserve, and/or distribute annotated biospecimens and associated medical data to institutionally approved, investigator-directed biomedical research to discover and develop new treatments, diagnostics, and preventative methods for specific and complex conditions.
To collect, preserve, and/or distribute annotated biospecimens and associated medical data to institutionally approved, investigator-directed biomedical research to discover and develop new treatments, diagnostics, and preventative methods for specific and complex conditions.
Medical Conditions:
ALS
Related Conditions: ALS
Sex/Gender: Male & Female
Age: 18 Years to 85 Years
Enrolling Now!
Alzheimer’s Disease
Study ID 259
Safety and Efficacy of Allopregnanolone (Allo) as a Regenerative Therapeutic for Alzheimer's Disease: Multicenter, Double-Blind, Randomized, Placebo-Controlled, Phase 2 Clinical Trial
A phase 2, double-blind, randomized, placebo-controlled clinical trial to evaluate the safety and efficacy of Allopregnanolone as a regenerative therapeutic for Alzheimer's disease.
Medical Conditions:
Alzheimer's Disease
Related Conditions: Alzheimer's Disease
Sex/Gender: Male & Female
Age: 55 Years to 80 Years
Enrolling Now!
Study ID 288
A Seamless Phase 2A-Phase 2B Randomized Double-Blind Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients with Early Alzheimer’s Disease
The purpose of this study is to learn more about the safety, effectiveness and tolerability of the study drug called Benfotiamine which may delay or slow the progression of the symptoms of early Alzheimer's disease.
Medical Conditions:
Alzheimer's Disease
Related Conditions: Alzheimer's Disease
Sex/Gender: Male & Female
Age: 50 Years to 89 Years
Enrolling Now!
Chronic Low Back Pain
Study ID 299
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Retatrutide Once Weekly in Participants Who Have Obesity or Overweight and Chronic Low Back Pain (TRIUMPH-7)
The main purpose of this study is to evaluate the efficacy and safety of retatrutide in relieving chronic low back pain in participants who have obesity or overweight. Participation in the study will last about 80 weeks.
Medical Conditions:
Chronic Back Pain
Related Conditions: Chronic Back Pain
Sex/Gender: Male & Female
Age: 18 Years and Older
Enrolling Now!
Diabetic Neuropathy
Study ID 295
A Phase 3, Randomized, Double-blind, Placebo- and Active-Controlled Study of the Efficacy and Safety of Suzetrigine in Subjects with Pain Associated with Diabetic Peripheral Neuropathy
The purpose of this study is to evaluate the efficacy, safety, and tolerability of Suzetrigine (SUZ) in participants with pain associated with diabetic peripheral neuropathy (DPN).
Medical Conditions:
Diabetic Neuropathy
Related Conditions: Diabetic Neuropathy
Sex/Gender: Male & Female
Age: 18 Years to 80 Years
Enrolling Now!
Study ID 296
A Phase 3, Open-label Study Evaluating the Longterm Safety and Effectiveness of Suzetrigine in Subjects With Pain Associated With Diabetic Peripheral Neuropathy
The purpose of this study is to evaluate the long-term safety and tolerability of SUZ and long-term effectiveness of SUZ in treating pain associated with DPN.
Medical Conditions:
Diabetic Neuropathy
Related Conditions: Diabetic Neuropathy
Sex/Gender: Male & Female
Age: 18 Years to 80 Years
Enrolling Now!
Obesity
Study ID 299
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Retatrutide Once Weekly in Participants Who Have Obesity or Overweight and Chronic Low Back Pain (TRIUMPH-7)
The main purpose of this study is to evaluate the efficacy and safety of retatrutide in relieving chronic low back pain in participants who have obesity or overweight. Participation in the study will last about 80 weeks.
Medical Conditions:
Obesity
Related Conditions: Obesity
Sex/Gender: Male & Female
Age: 18 Years and Older
Enrolling Now!
Gout
Study ID 303
A Phase 3, Randomized, Double-Blind, Multicenter Study to Evaluate the Efficacy and Safety of Dotinurad Compared With Allopurinol in Adult Participants With Hyperuricemia Associated With Gout
The primary objective of this study is to evaluate the efficacy of dotinurad in lowering serum uric acid (sUA) at Week 24 compared with allopurinol in adult participants with hyperuricemia associated with gout.
Medical Conditions:
Gout
Related Conditions: Gout
Sex/Gender: Male & Female
Age: 18 Years to 75 Years
Enrolling Soon!
Study ID 304
A Phase 3, Randomized, Double-Blind, Multicenter Study to Evaluate the Efficacy and Safety of Dotinurad Compared With Allopurinol in Adult Participants With Tophaceous Gout
The primary objective of this study is to evaluate the efficacy of dotinurad in lowering serum uric acid (sUA) at Week 24 compared with allopurinol in adult participants with tophaceous gout.
Medical Conditions:
Gout
Related Conditions: Gout
Sex/Gender: Male & Female
Age: 18 Years to 75 Years
Enrolling Soon!
Chronic Knee Pain
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